Cutaneous toxicity issues during chemotherapy


Chemotherapy can induce alterations of the integumentary system. These could be generalized or localized reactions and therefore are often manifested on the skin, its appendages, and mucosal surfaces.

Cutaneous reactions vary in site, onset, severity, and duration depending on the type of cytotoxic agent used. Cutaneous toxicity is usually transient since the skin regenerates its epidermal layer in Thirty days.

Unless the cutaneous reactions are severe, involving tissue necrosis, cutaneous toxicities eventually resolve. However, cutaneous reactions should be carefully evaluated simply because they can severely modify the patient's both mental and physical health.

Cutaneous toxicity can transform the skin's capability to protect your body against fluid loss, can transform temperature regulation, and may diminish sensations of pain and touch.

Since most cutaneous manifestations are visible, they are able to possess a tremendous impact on the patient's self-image and just how others perceive her or him.

Apart from using cytotoxic agents, especially at high doses, potential causes for cutaneous symptoms are infection, cutaneous malignancy, metastatic spread, graft-host interaction, nutritional disorders, along with other drugs, for example antibiotics and analgesics. The chemotherapy cutaneous reactions range from the following:

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