Lip lesions: Vermilion and commissure reconstruction


Primary Closure

Lip lesions are typically due to trauma, infection, or tumors. Defects under one-fourth to one-third of the total lip length can be closed primarily. This involves the apposition of the lateral margins from the wound on sides and direct layered closure. The muscle is approximated with interrupted deep absorbable sutures. The white roll is closely approximated and then the labial mucosa and vermilion are closed. Finally, your skin is closed with fine nonabsorbable sutures.

Ideally, primary closure should cause minimal aesthetic and functional deformity; however, it can sometimes result in decrease in the oral aperture as well as asymmetry of the involved lip. Furthermore, primary closure in the upper lip could be problematic because opposing the edges of a big wound may create unfavorable distortion from the philtrum.

Vermilion Reconstruction

The vermilion spans the entire length of the oral aperture, becoming increasingly narrow and tapering laterally since it approaches the commissure on sides. It forms the transition zone between skin and mucosa of the inner mouth. Defects involving the vermilion ranges from superficial, such as leukoplakia in which there is limited compromise from the integument, to significant, in which tissue deficit extends to deeper muscle and mucosal tissue. Although small defects of the vermilion can be primarily closed or left alone to heal by secondary intention, larger defects require reconstruction.

Precise alignment from the vermilion-cutaneous margin on both sides ensures a curvilinear appearance from the border and avoids step-offs or lip notches after healing. The standard labial mucosal advancement flap can replace vermilion resections that span the whole length of the lower lip. The mucosa on the buccal top of the lower lip is undermined and advanced to the previous mucocutaneous junction.

Maximal use of blunt undermining helps to preserve sensory innervation of the vermilion-to-be. Additional advancement can be achieved using a transverse incision in the gingivobuccal sulcus and in the process creating a bipedicled mucosa flap based laterally. Extensive flap mobilization usually results in an insensate flap.

A notched appearance from the vermilion can result from scar contractures or vermilion volume deficiency (because of previous surgery or trauma). Scar contractures can be released having a Z-plasty. This process recruits vermilion tissue on each side of the scar to functionally lengthen the scar in the antero-posterior and supero-inferior direction. A notched appearance because of volume deficiency could be corrected having a local musculomucosal V-Y advancement flap.

The next option of donor tissue is a flap from the ventral top of the tongue but it's less than ideal due to color mismatch. Pribaz described the facial artery musculomucosal (FAMM) flap, which is a based on the facial artery and is used to reconstruct defects involving vermilion, lip, palate and a host of other oral structures. Labia minora grafts may also be used to reconstruct the vermilion.

Commissure Reconstruction

Commissure deformities often result from electrical burns, trauma, or reconstructive lip surgery. For post-burn commissure contractures, splinting techniques have reduced the need for surgical correction. Nevertheless, repairing deformities that don't react to conservative measures remains complex.

The intricate network of adjoining perioral muscle tissue in the modiolus (that is crucial for oral competence and facial animation) is nearly impossible to reconstruct. Furthermore, the contralateral commissure may be the gold standard of comparison when looking for the outcomes of the unilateral reconstruction, thus leaving little room for discrepancy.

Various approaches attempt to repair mucosal defects involving the commissure including the simple rhomboid flap, in which intraoral mucosa is advanced to reconstruct the commissure angles after an incision is built to widen the commissure laterally. The tongue flap may also be used when the mucosal defect is thick in the region of the commissure. Despite many proposed techniques, commissure reconstruction remains a hard task and attempts at reconstruction often yield poor results.

Legal Disclaimer

Our website is not responsible for the information contained by this article. Articleinput.com is a free articles resource thus practically any visitor can submit an article. However if you notice any copyrighted material, please contact us and we will remove the article(s) in discussion right away.

Note: This article was sent to us by: Keith Hayes at 02142011

Related Articles

1. The hypothalamus and other neuronal markers
To date, the GHS-R has been localized at the mRNA level by a combination of in situ hybridization, RNase protection and RT-PCR techniques. Thes...

2. Clinical evaluation in humans
A comprehensive search was initiated for GHS-R related GPC-Rs. Overall, this search was undertaken to further elucidate the mechanism of action...

3. Regulation of synthesis and secretion
The original growth hormone-releasing peptide (GHRP), which was synthesised by Bowers and named GHRP-6, stimulates GH secretion in a relatively...

4. Identical effects on hydrolysis and secretion
Growth hormone secretagogues (GHSs) release growth hormone (GH) via both the hypothalamus and the pituitary gland, and also stimulate ACTH and ...

5. Positive effect on human adenoma cells
As corticotroph adenomas are usually very small compared to other hormone-secreting adenomas, it is extremely difficult to study these tumours ...

6. Possible changes in the activity of arcuate neurones
The pulsatile pattern of growth hormone secretion from the anterior pituitary gland reflects a changing balance in the output of two hypothalam...

7. Neurones are neuroendocrine cells
The first recordings of changes in electrical activity following GH secretagogue administration were incorporated into a series of experiments ...

8. Acute effects on feeding behaviour
The discovery that the GH secretagogues activate NPY neurones led us to consider what is known about these neurones that might help explain wha...

9. A model of pituitary desensitization
Administration of GHS induces a rapid increase in plasma GH levels in a broad range of animal species i.e. rat, monkey, sheep, pig, chick, stee...

10. Fluctuations are organized into pulses
In all species studied thus far, including man, growth hormone (GH) secretion is pulsatile. Using sensitive GH assays and frequent blood sampli...