Male infertility can be reversed by an Omega 3 essential fatty acid


The February 2010 issue of the Journal of Lipid Research published the outcomes of a study in the University of Illinois, the first to show an immediate role for that Omega-3 essential fatty acid docosahexaenoic acid (DHA) in sperm formation.

University of Illinois at Champaign researcher Dr. Manabu T. Nakamura and associates used mice genetically modified cannot produce certain crucial essential fatty acids necessary to produce sperm, including DHA. These animals cannot form sperm and therefore are infertile. The genetically modified mice and normal mice received diets supplemented with arachidonic acid or DHA from weaning until 16 weeks of age.

Those animals receiving DHA were built with a breeding success comparable to normal mice, and showed normal sperm fertility and formation, instead of those that didn't receive DHA.

"In our experiment, we used 'knockout' mice that lacked the gene accountable for an enzyme important in making docosahexaenoic acid," explained Dr Nakamura. "In the lack of DHA, male mice are just infertile, producing few if any misshaped sperm that can't get where they need to visit."

"We checked out sperm fertility, shape, and motility and tested the breeding rate of success, and also the mice lacking DHA simply were not able to to reproduce," lead author Manuel Roqueta-Rivera noted. "It was very striking. Whenever we fed the mice DHA, each one of these abnormalities were prevented."

In the future, they continues to research DHA's effect on male potency. "We get hints from taking a look at sperm in the DHA-deficient animals by what kind of pathology we might be checking out and the polyunsaturated essential fatty acids are essential," Dr Nakamura said. "But we're still in the starting place in comprehending the mechanisms that are participating and that we need to complete more research in the cellular level."

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